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Symbol
Name
ID
Tirap
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
MGI:2152213
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
decreased B cell proliferation
decreased IgG3 level
abnormal macrophage physiology
abnormal dendritic cell physiology
abnormal level of surface class II molecules
abnormal cytokine secretion
abnormal interferon secretion
decreased interleukin-12b secretion
decreased interleukin-6 secretion
decreased tumor necrosis factor secretion
increased susceptibility to bacterial infection
Availability Mouse Genotype
Tirapm1Btlr/Tirapm1Btlr
Tiraptm1Aki/Tiraptm1Aki
Tiraptm1Medz/Tiraptm1Medz

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory